Integration of gene expression and microRNA expression

A microRNA plays a key role in the development of many cancers. It is known that a microRNA regulates multiple genes and a gene is also regulated by multiple microRNAs. It is also observed that the regulation of genes by microRNAs can be different depending on patients even though they suffer from the same cancer. Hence, it is an important issue to identify these complex relationships between genes and microRNAs in cancer. Our challenge is to identify modules representing interrelationship between genes and microRNAs by integrating these data sets.

Gene-microRNA Network